17-year-old Leon Wang finds 2 FDA-approved drugs that reduced Alzheimer’s-linked cell damage

A young student's research explored existing medicines for Alzheimer's disease protection. He identified two drugs, nintedanib and pirfenidone, showing protective effects in cell models. This drug repurposing approach offers a faster, less expensive research starting point. Wang's work highlights targeting APOE4 and brain blood vessel cell changes. His findings suggest further investigation into TGFβ pathway drugs is warranted.

By TOI Science Desk